Theodoros
Visvikis

PhD candidate, M4i, Maastricht University

Mass spectrometry imaging, spatial multi-omics, and the open-source software that brings them together.

Portrait of Theodoros Visvikis

Software

Python library that converts mass spectrometry imaging data (imzML and Bruker) into the SpatialData/Zarr format, so MSI can be analysed alongside other spatial omics data.

pip install thyra

All software and contributions

Recent

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About

I am a PhD candidate at M4i, Maastricht University, in the group of Eva Cuypers. I work on single-cell multi-omics data integration, analysis and management, and above all on bringing mass spectrometry imaging (MSI) into it.

MSI can add a breadth of molecular information to multi-omics, but only once its data fits into the frameworks the rest of the field already uses. Much of my work is the software for that: Thyra, which converts MSI data into the SpatialData format, and contributions to spatialdata, spatialdata-io and zarr-python.

Before the PhD, I studied analytical chemistry at the Maastricht Science Program, with a bachelor's thesis under Maarten Honing on liquid chromatography, mass spectrometry and ion mobility spectrometry. I then spent a year in his group finishing that work and developing flow chemistry sensors for process analytical technology. For my master's in Molecular Imaging & Engineering at Maastricht University, supervised by Ron Heeren and Maarten Honing, I used MSI to map the spatial molecular heterogeneity of plant-based meat alternatives, and picked up machine learning for imaging data along the way.

You can reach me at my university address.